Causes of Uterine Cancer

The formation of uterine cancer generally begins in cells that make up the lining of the uterus (endometrium). That is why uterine cancer is also often referred to as endometrial cancer. The cause of the formation of uterine cancer until now is still a debate among experts. Even so, there are several theories that mention the possible causes of uterine cancer. In addition, conditions such as obesity, age, to hormones, are considered to be risk factors for this type of cancer. Find out more on

Until now, the cause of uterine cancer is not known with certainty. Some experts suspect, high levels of the hormone estrogen in the body can be the cause of this disease. When the balance of these two hormones is disturbed, the endometrium (uterine lining) can undergo changes. Increased estrogen levels without accompanied by increased levels of progesterone, can make the uterine wall become thickened, thus potentially increasing the possibility of cancer. To be sure, genetic mutations can cause normal cells in the endometrium, turn into abnormal. These abnormal cells can multiply rapidly and then form tumors. In severe cases, these cells can spread to other parts of the body.

Although the cause of uterine cancer is not yet known with certainty, several conditions are believed to increase a person’s risk of this disease.

As we get older, the risk of uterine cancer in women will increase. Based on data submitted by Cancer Research UK, most patients with uterine cancer are women aged 40-74 years. Most women who are diagnosed with uterine cancer, are those who have experienced menopause. Only a small percentage, or about one percent of cases of uterine cancer occurs in women under the age of 40 years. In addition, women with a genetic disorder called Lynch syndrome, have a greater risk of developing uterine cancer at a young age, when compared to women in general.

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